Are weed and mushrooms at all similar in how they make you feel?

By that I mean, the physical effects on the body like higher heart rate, dry mouth, etc?

I tried weed once, first and last time, in brownie form (I took too much), it fucked me up. But the thing I hated most was the vasodilation, my breathing and heart rate and sweating. My heart rate is usually around 45bpm resting and when my heart rate goes up above 100bpm (unless I'm exercising) I get really anxious, which in turn makes it worse like a catch-22.

So I'm just wondering.

Will I feel (even slightly) similar to how I felt when taking weed?