Any negatives with a full remote offer close to home?

I'm currently interviewing for a fully remote position with a company based on the east coast(USA), but they have a facility about 45 miles from my home. Commute would be about 2 hours in rush hour each way which I have no desire to do. When I spoke with the recruiter I was told only periodic training requires in person(for which the company covers all travel and lodging expenses) and the position was opened up from in office role to full remote in the US to capture more qualified candidates. I'm comfortable with training and periodic session in office as stated, but commuting even 2-3 days a week indefinitely seems exhausting.

It's a great opportunity, but I have no desire to commute this far. My current commute is about 10 miles in a hybrid role. I have a final interview tomorrow and hoping for an offer. What questions should I be asking other than if this role will remain fully remote or if I need to be concerned with a change?