Questions about M365 Quarantine usage

First off, I'm one of those "inbox zero" type of people.

How do you all utilize the quarantine? If something is an actual threat, do you delete it? When you delete it, do you "temporarily" delete it (the default) or check the "Permanently delete" checkbox? What happens when you "temporarily" delete it? This seems weird to me.

I think my reluctance/confusion comes down to the fact that as a rule I don't "delete" anything. I like data. All feedback appreciated.