Webmail and Only Webmail

I'm looking for a simple (but great) webmail service to replace gmail. I'm not _that_ privacy conscious (a little), but I want a fresh start and to compartmentalize my accounts. I plan on mainly using thunderbird/apple mail, but easy webaccess is very important.

I already use radiCale for contacts and calendar. I don't want a full suite -- just email done _really_ well. Doesn't have to be free. I would host it myself, but apparently hosting email is too hard to do and secure to be worth it.

Any ideas?