Has anyone noticed and increase in symptoms with Aspartame?

I am a Diet Coke addict and there are lots of reasons it can exacerbate POTS but I started wondering if the actual chemical aspartame could be a problem. I know that epileptics need to stay away from it. I switched to Diet Pepsi (aspartame free version) when they took out aspartame from their formula and I was fine until I wasn't----6 months later. When I looked at the bottle Pepsi had put the aspartame back in. The lobbyists for aspartame are big and I never see anything negative about it....however, this news got me thinking about the effect that artificial sweeteners might play. https://www.medicalnewstoday.com/articles/common-sugar-substitute-may-affect-brain-and-blood-vessel-health