I need advice for DDDA

Hello fellow Arisens, I am doing my second attempt at my 1st playthrough of DDDA, (first run failed because PC died) and I would like some advice to stop me from getting overwhelmed, which is very easy for me in games like this.

Essentially I am asking if there is anything important I should know that anyone here wishes they knew on their first playthrough. No spoilers please.

Thank you in advance