Workspace App LTSR 2402 window won't open (not a .NET crash)

This past weekend we updated our infrastructure to LTSR 2402, clients were already using the LTSR 2402 workspace app. An entire new environment and then a DNS entry swap.

Now we have some users where the workspace app window won't appear. Apps will launch successfully from start menu icons and from a web interface, it's just that the workspace app window won't load to allow users to launch apps that way. When I right click on the system tray icon, instead of an "Open" menu option, I have "Refresh" instead.

It seems (though I'm not 100% sure) that it affects anyone that does a new install and connects to the new site and/or if the workspace app settings are reset. Users that were connected to the old site and just switched over without any reinstalls or resets seem to be ok.

Anyone have any insight into what that might be? I'm assuming it's a setting on the store but I can't find anything about it and my Google fu is failing me.