POPH30003 and 30004, how bad is it?

I'm a biomed student and because i started mid year i have to do these subjects in my 2nd year if i want to do the POPH major, but then that means i have to do it with MCB. Ik MCB is difficult, are those 3rd year bad as well? do yk ill be able to do well in all 4? or should i consider other majors?