Agmatine interactions

To assist reduce my tolerance to elvanse, I would like to try agmatine. Because the psychiatrist believed I would be a quick metaboliser, I was previously moved from Adderal to Elvanse a few months ago. I used to take 40 mg of Elvanse in the morning and another 40 mg four hours later. As far as I'm aware, this is by no means a low dosage, and while it did work for a while, I'm starting to have some second thoughts about its efficacy. It's been about a year since I started taking stimulants. I do not wish to keep increasing the dosage. I'd like to test agmatine because of this. But I'm concerned about potential drug interactions with my sleeping pills. I also tried ashwgandha, l theanine and moda from ndepot, now and highstreetpharma but it was giving me anxiety. I am prescribed 100mg of pregabalin for RLS and 25-50mg of quetiapine for sleep in general. I have read that as a broad NMDA antaginist, agmatine can also alter gaba pathways, which the sleep meds have an interaction with.

Can agmatine potentially lower the effectiveness of my sleeping meds? If that's the case I would reconsider this supplement. Any other NMDA antagonist recommendations to help lower tolerance to adhd stimulants, without negative interactions to the sleeping meds I'm using?