Can’t Eat Enough/GI Issues on 5mg

Side Effects

Hey all, in my fifth week (4x2.5, 1x5mg). Took the first 5mg shot on Monday, and it’s been 96 hours of diarrhea and cramping. Anything I put in my stomach is almost instant GI issues. As a result, I’m barely getting to 800 calories a day although I am downing 3L of water on average.

Pre-Zep, I struggled to eat and drink anyway with ADHD and Vyvanse. Before Zep, I could maybe get to 2,000 calories on a good day or 1,500~ calories when I forgot to eat. On that, I got up to 215lb.

First four weeks on 2.5mg, if I hit 1,200 calories, that was a good day. My appetite was just gone, but little to no GI issues. Went from 215 to 201.

Now, I can’t really get down anything more than 800-1000 calories and that’s constant diarrhea, half a bottle of Pepto, and Gas-X.

I’ve also had GI issues for years, but really only with dairy and protein-related drinks (powder or the liquid kind). This now feels like everything is a GI issue, even bland chicken and broccoli.

Is the only solution to just slug through with anti-diarrheal meds, or can I go back to 2.5 and just live there? 5mg feels untenable right now.

Thanks for any advice!

Posted Jul 4, 2025, 1:17 AM UTC

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