Possible RAD-140 use LONGTERM for longevity and performance boost while on TRT

Ryan Russo (I know he’s schizo, but hear him out) talks about the use of RAD-140 longterm for peformance + longevity benefits while taking TRT in his new video. IF it is theoretically tolerable long-term.

He discusses using RAD-140 theoretically long-term at a low dosage alongside TRT.

Benefits:

• enhance muscle and strength gains
• provide neuroprotective effects~ protect the brain and specifically the hippocampus
• less estrogen and DHT conversion as you can lower the TRT dose when implementing the RAD
• for the reason above, you could therefore mitigate prostate issues as well
• ability to modulate the overall androgen receptor pinging to the brain while you have (theoretically) neuroprotective effects of RAD-140 on the brain~ theoretically an easier to maintain CNS
• densifies the bones
• mental aggression & sharpness

Negatives:

• skews cholesterol (but so does testosterone), and this can be combatted
• no long term data
• not bio-identical to testosterone, aka SHBG does not recognize it and it is not transported around correctly
• more systemic inflammation?
• androgen receptor remapping~ needing to add in more androgens over time

Thoughts on this?

Neuroprotective effects of RAD140: PMID 24428527

High-dosage data on RAD140: PMID 40158703