Sounds familiar?

Getting straight to it ( boyfriends uncle) he’s had issues with his liver and has been going to the hospital for the past half year maybe just for check up’s. Everything was normal till recently he’s been having weird issues/ symptoms. It started when he woke up and has peed himself, he was saying the same 4 numbers , didn’t let anyone touch him and didn’t really care or didn’t even know his own family, and was just saying he was burning. He said he doesn’t remember that happening and recently he’s had a really bad fever and was talking gibberish again. Tried taking him to the doctor but he gets really mad / bothered in those episodes. Anybody know or suspect what could be happening? Again He’s been going to the doctor regularly ever since his liver problem.