Slow COMT and slow MAO A

Hi, so I have had my genetic profile come back with the above variations. I have issues handling stress, I’m irritable, anxious, just an all round lovely person atm 🙃 my throat feels like it closes up a little with certain foods, I have body twitches and my mood around my period is not good.

Could this be histamine issues caused by lack of estrogen clearance from my slow COMT and inability to clear histamine properly due to slow MAO A? Or is that too simplistic? I also have flares and the absolute worst tummy pain from miso and tempeh which are high histamine. TIA