If I’m concerned about Progesterone -> DHT conversion, how long should I take Dutasteride before starting Prog again?

Previously when taking Prog I was able to confirm with bloodwork that it was raising my DHT. It wasn’t a ton (< 3ng/dl off Prog vs 8ng/dl on), but any conversion was enough to scare me into either quitting Prog altogether or trying to block the conversion. Since I’ve heard Dutasteride should be sufficient for fully blocking that 5-AR conversion I’ve just started taking Avodart this morning, but I know that Dutasteride also takes a while to build in the system before it’s fully effective.

So my question here is how long should I take it before I can safely reintroduce Progesterone without worry of that conversion?

Posted Jul 19, 2025, 7:50 PM UTC

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