Does anyone else have chronic migraine syndrome plus Protein S deficiency or another coagulation disorder?
I've had chronic migraines my entire life and tested positive for Protein S deficiency two decades ago after my daughter had her first PEs. My daughter, my brother, my mother, my grandmother and many of my other relatives have Protein S deficiency so my diagnosis came as no surprise.
I had my first clot (DVT) last year and have been on Eliquis since. Everybody else in my family with Protein S deficiency is an Eliquis lifer so I'm resigned to being one, too.
Virtually all of them also suffer from migraines.
A few studies have been done that indicate a higher incidence of migraines in people with Protein S deficiency than those without. IMO there's definitely a link.
I'm curious if others have the same two disorders.
Posted Jul 24, 2025, 4:31 PM UTC