Skipping MOTN timing

How long can you all go in between pumps at night? I’m 15 weeks pp and exclusively pump. I pump at 10 pm before I fall asleep and then usually at 4 am (so 6 hours later). For people that skip the “middle of the night” pump, do you just pump at midnight and then 6 am again or what am I missing? I haven’t really tried to go longer between pumps as I’m afraid of supply drop. But pumping at 4 am is starting to kill me

I pump around 5-6 times a day, 15-30 min, every 4-5 hours during the day, 6 at night, and make about 25-30 oz total.