B4ms VS B4as v2 - for running .net web applications

So we've been currently using a general purpose B4ms VM as a windows server to host our AspNetCore applications. We're quiet comfortable with the current configuration and it works very well for us. Since our reserved instance is going to end soon, we've been thinking about upgrading the system, since our applications have grown significantly.

Upon some basic research, I found that the B4as offers more performance and is significantly cheaper, since we're based in India. This could be a great solution for us as this would reduce cost and give us more performance.
While this looks great on paper, there is still some skepticism within the team regarding the AMD CPUs, as some have heard or seen issues being present with AMD systems, both in consumer electronics and server hardware.

We would not like to take any risks with the VM server. I'm quite new to these things myself, so any help and advice would be appreciated. Thanks.