Why do most downers give me energy while some uppers make me tired?

Simple question, sometimes when I take benzos, yerkylators or more downers, but especially those, I get a big boost of energy (obviously in high doses it sedates me), while taking certain stimulants make me tired (not all of them, I love stimulants and I lot of them do give me energy, but some don't)

Just for context, I'm diagnosed with ADHD, MDD, GAD, so maybe that has to play a role?

Any of you guys experience this too?