Mod that lets you "beat" POI's so they stop randomly generating

What if it was possible to "beat" a POl, thus stopping it from randomly being generated? Beating the POI might be finding the high level loot, unlocking the secret room, finding all of the lore elements (journal entries, items, etc.), or killing the mini-boss? Some of the POl's have little stories in them.

Once the player beats the POI, it remains permanently fixed in whatever zone it's generated in, sort of like an outpost. If it isn't beaten, it'll get generated again to give the player another chance.

I know there are over 100 so it would take some time. If I ever get around to learning modding, I might get started on it myself.

Thoughts?