So the Supernatural Multiverse, how does it work?

So Chuck and Amara were the first two original beings, before Chuck made the dimensions it was just those two, okay, I get that.

Chuck got lonely and started creating things, eventually creating the archangels, who helped him take down Amara and seal her in the Mark put on Lucifer.

Now here is the problem. We know there are at least two different Michaels and two different Lucifers. Apocalypse world had a showdown and that Michael killed that Lucifer. Base world Lucifer died and base world Michael is in the cage.

How do the archangels interact with the multiverse and taking down Amara? Since they were unaware of the multiverse they didn't all fight together and they don't exist outside the dimensions like Chuck and Amara. Are there multiple Marks since there are multiple Lucifers and Cains? Could Amara have been unleashed from any of the Marks being destroyed or was the power of the Mark over Amara just in his favorite universe? The latter does make some sense considering there is only 1 Chuck and 1 Amara, but which set of Archangels helped take down Amara? Since it was the Mark that corrupted Lucifer and he was cast down in at least 2 universes so we know it existed and affected multiple people at the same time.