Significant short term memory and restfulness improvements on meds in my early 20s.

QUESTION

I was diagnosed with ADD in my early 20s (~10 years ago). During that time they had me cycle through a few different medications at different dosages. Of those I found that methylphenidate was the most effective, though it had the following effects:

  1. Sensory amplification
  2. Heart rate increase
  3. Personality changes (I was much more serious and focused, whereas normal for me is to joke a lot, probably too much haha)
  4. Significant memory improvements. I don't have a very good short term memory, and almost no visual memory, but on the methylphenidate, I could play back things said earlier in the day verbatim in my head. I don't consider myself having issues paying attention, so I think this might have improved my working memory or short term memory.
  5. Restfulness improvements - most of my life I would wake up feeling tired and had a hard time getting out of bed unless I had a reason (job, school, etc...). On the methylphenidate, when I woke up I was ready to go and could get out of bed immediately.

I decided not to continue on meds at the conclusion of the trial.

Later on in my early 30s, I decided it would be helpful to be better rested and improve my memory, but upon trying methylphenidate again, I noticed none of the early effects other than the increased heart rate.

Has anyone else, observed an effect like this? If so, were you able to resolve it?

I'll note that I have some history of inflammation, but nothing that majorly impacts my day to day.

Posted Aug 31, 2025, 12:12 AM UTC

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