Affirma results-- doc says I need surgery even though the chances are mid?
Hi everyone, so here's my story: presented with pain in my neck (which is unusual for cancer), ultrasound revealed three TRAD5 nodules. Doc biopsied two of them. One of them had insufficient cells for the test and needs to be redone. The other one came back category 3, which my doc said made it a 15% chance of cancer. To make things more confusing, he said that the pain and numbness I was experiencing in my neck was "unrelated" and had another cause, so I'm seeing an endocrinologist at the end of the month.
Then my Affirma test came back for that (painful) nodule and was classified as "suspicious" although none of the mutations and markers were noticed. My doc said this now raises my chances to 50% for that nodule and it needs to come out. I asked to redo the biopsies on the right two nodules (one of which is very large) so we can maybe save half the thyroid.
I guess my questions are... is it normal to always have surgery for classification 3 and Affirma suspicious (overall 50% chance)? Should I be getting a second opinion for that nodule and consider doing a watch and wait approach? Is it worth it to try and fight to keep the right side of my thyroid, or should I just do the total if that comes back indeterminate at all? What should I be thinking about as I make this decision?
The pain is also starting to resolve after 3-4 months of daily pain, so I'm not sure what that means either...
Posted Sep 2, 2025, 3:27 PM UTC