Neville Longbottom(Harry Potter) - (Permanent) Initially the butt of jokes for almost 6 books, he took up Harry's role as the lead rebel in Hogwarts after the trio were forced to go into hiding. He did a pretty good job at it even accepting punishment from the new staff knowing he's doing the right thing. He was even the one to cut off Nagini's head, making sure Voldemort is truly mortal again.

Bennett(Genshin Impact) - (Temporary) Due to recent magic ley line reveals, turns out Bennett's extreme bad luck was due to not being in tune with his homeland. During an event story where he came back there after years away from it, he experienced his first genuine average day in his whole life. He was so overwhelmed about not being a screw up that he and the Traveller actually cried tears of joy.

Sakura(Zombieland Saga) - (Temporary) Sakura's a partially amnesiac zombie tasked with other zombies to form an idol group to save Saga. Knowing she can have a chance to live out her dream of being an idol when she was alive, she was the one most active at trying to be an idol even though the others, while initially apathetic, were mostly better than her while she was stuck as the unlucky one. She eventually unlocks her full memory after getting hit by a truck(again) and remembers how much her bad luck cost her every dream she had which caused her to go into depression with the other zombie idols getting worried for her and the situation being treated seriously. Eventually they managed to get her back to her outgoing self in time for the finale.

The one who's the butt of the joke temporarily or permanently loses that trait.