more depressed - thoughts?

hi all,

ive been on zoloft 50mg for about 2 weeks now. also taking wellbutrin 150mg xl for over a year. while my anxiety is at an all time low, my depression has gotten worse - sleeping in later, increased thoughts of self harm are the main two symtpoms. there are lifestyle choices that could be influencing this - i use thc and alcohol recreationally on a regular basis. is this the wrong med for me? should i wait and make some lifestyle changes first? what are your experiences?