Want to run spec-ops vampire hunter style game, looking at GURPS

I had the idea for a video game that I want to translate into a ttrpg short campaign, and I saw GURPS mentioned, so I gave the lite fourth edition a brief glance. It seems solid and adaptable for what I think I need, what would I need in order to run a short campaign where my players are spec ops entering Washington DC to rescue a fictional president from a vampire invasion?

Advice on how to run GURPS, supplements that I should or should not use, other TTRPGS that might be better suited, and anything applicable is welcome.