How do I interpret a lack of a reply from a prospective advisor?

Hey there! I’m an undergraduate senior applying for PhD programs in the social sciences this fall. Last Wednesday, I had a Zoom call with my dream advisor. I made a huge mistake! She was my first prospective advisor I called with, so my answers to her questions weren’t great. I think I rambled and I worry she was put off by my vagueness.

I sent her a follow-up email the next day (Thursday morning) with a thank you and a few extra questions. She hasn't replied to it. She’s on research leave and traveling, but she had a decent response rate before.

I’m wondering if and when I should take a lack of a response from her as a sign that she’s not interested in taking me on as a student. For reference, the program I’m applying to expects you to coordinate with an advisor ahead of time as you immediately start working with them upon arrival.

In sum, what do you all think? I’ll admit, I’m quite nervous and I assume I'm currently overthinking things. That being said, I’m sure you all can empathize with struggling due to replies (or lack thereof).