Am I taking my pills wrong?

Ive been on hormones for just short of a year now. If noticed some changes but not as much as I want. I take 4mg of estrogen and I think 40 of Spiro (im too lazy to check rn) my doctor told me to take half the dosage in the morning and half at night. Ive been lazy and do it all at night because I can barely remember to do that even with alarms. Is this negatively affecting me more then I think?

Also secondary question? What do people men when they say they DIY hormones? I dont get it