Started 3 days ago - normal side effects?

Question

Hey, everyone! Had mild anxiety my whole life but my therapist suggested I start Zoloft recently because of ongoing medical problems with similar symptoms as my anxiety. Just started on 25mg about three days ago.

I’ve been having some weird side effects and wanted to know if this was normal. The first day, I took it around 1am and had pretty bad derealization and severe anxiety spikes till late afternoon. The second day, I took it around 9pm and was just a little dizzy the morning but it passed. Last night, I took it at 10:15 and was almost asleep when the anxiety kicked in. Barely slept and I kept waking up with horrible anxiety and severe nausea throughout the night. Woke up this morning and had severe anxiety until about 9am. Pretty bad nausea and dizziness throughout the three days but those are symptoms of my other ongoing medical problems as well and my anxiety so I can’t tell how much is normal.

Anyone else had these severe anxiety spikes and bad nausea? It’s absolutely horrible. I’m on these meds to prevent further anxiety but when I’m on them, I’m constantly on edge. Also has led to me becoming terrified to go to class or my dorm or literally anywhere that isn’t my home, which is exactly what I was trying to prevent by getting on these meds.

Posted Oct 28, 2025, 4:47 PM UTC

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