What are the Podcasts You Love Despite it's Subject Material?

I've discovered that a few of my favorite podcasts are about subjects I don't really care about. For me, I love listening to smart funny hosts on obscure topics. For example, there's an amazing wine podcast I listen to every week despite not really being into wine. I just think the hosts have great chemistry.

So, what podcasts so you listen to that are great, despite the topic?