How risky is it reputation wise to accept a role then back out?

I got laid off in October and immediately started treating job searching like a full time job. Things started slow but really picked up the last week. I just received one offer from a company with a good reputation but it pays less than other positions Im going for. I also find the product a little boring. I had what I thought was a final at another company yesterday but for one last step they want me to meet with their CEO early next week. There's also some other earlier stage ones ive had that pay more and I find the product more interesting.

I hate the idea of capping my earnings for the next 2-3 years unnecessarily but also I only have one real offer in hand. The start date wouldnt be for another 3-4 weeks so i could technically accept then back out if one of these other ones work out. But how risky is that? Has anyone here been in that situation or know anyone who did that and it royally screwed them later?