How do you create your synergies? And what are some of your favorite synergies?

So I think you (typically) spend the first part of your spire journey desperately seeking out damage in order to take on elites. But after that, you'll need to find some sort of synergy amongst your cards and relics and a way to survive long enough to play it.

How do you create your synergies? And what are some of your favorite synergies so far?

My "go to" approach to creating synergy is to ask myself "What do I have a lot of sources of?" and "What works well with that". For example:

I have a lot of sources of <strength>, what works well with <strength>?

I have a lot of sources of <discard>, what works well with <discard>?

I enjoy the synergy of Corruption + Dead Branch.

I also enjoy Mummy Hand + Heatsink + Bird-Faced Urn then just a bunch of powers. (At least until I run into awakened one...)