Second dose of 2.5mg and wiped out for 8 days
Hey all
I’m just had my second dose of Mounjaro 2.5 mg. First dose knocked me hard with nausea, fatigue, sulfur burps, no appetite etc, but I expected that. What I didn’t expect is that I’ve basically felt wiped out for 8 days straight. I’m talking dizzy, nauseous waves, low energy, hoarse voice, and feeling too sick to work.
I’m tracking macros and eating high protein, moderate fat, lower carb. Calories have been reasonable, around 1500 to 1800.
I also might have a virus, but I can’t tell where the medication ends and where being sick begins.
I also made the genius decision to taper off an SSRI (Lexapro) I was taking at the same time. Probably not a good idea.
Second dose brought the nausea back instantly. I get short windows of feeling ok, then it hits again.
Is being knocked out for 8 days after a 2.5 mg dose something other people have experienced, or is this a sign I should reduce the dose or pause?
I am loving the results of the medication but these side effects are killing me.
Any advice appreciated
Posted Dec 1, 2025, 3:03 AM UTC