How would you execute a green screen interview?

I have a web-series where I take comedians to joke and learn about fine art at museums. I started in Colorado but I just moved to NYC. Recently, a local art gallery reached out to me about doing Comedians Talk Art to promo their show and I suggested a virtual option where I interview the artist.

My idea is to do a front facing video of myself (with the art as the green screen background) and then have the artist reply to my question recording their reply on their front facing camera with the same green screen art behind them. It seems like apps like Instagram only let you green screen within the app. Is there a more seamless way to do my idea? I think I can do it as a zoom interview but the layout feels kinda tacky and I don't know that I can evenly green screen the art. I hope this makes sense.