Permanent Brain Damage

My 25 year old has used MDMA, I'm not sure how much over the years, in college, and so forth.

She recently had a bad experience and says she's not doing any drugs again. She never did pot, mushrooms don't affect her, she cut way down on drinking -- can take it or leave it.

Because she came very close to being date raped last month, she says no more MDMA for her!

The sick part is that her boyfriend was right there, high as a kite on several substances at once, and didn't do a thing, while the other guy was groping her. Then he turns around and accuses her of cheating on him.

She can't see the fucked-upedness of this scenario and stays with him, like the worst kind of co-dependant.

My concern is, how real is it that there is permanent brain damage from using it?