Advice needed for chaotic toddler classroom

Hi, everyone. I started working as the lead teacher in a 2-3 year old classroom (up to 10 kids at a time) about 6 months ago, and their behavior was manageable until recently. However, in the past week, my classroom has become steadily more chaotic. Children are running, screaming, throwing things, hitting, pushing, biting, etc. I'm not sure why I'm seeing so many misbehaviors all of a sudden and nothing works: distraction, redirection, natural consequences, etc. I try to play with the kids and give them personalized attention, but they are defiant and don't listen to anything I say. Even putting their shoes on for lunch or laying down for nap is an epic struggle. Normally we go to the playground every day but the weather has been bad this week, so that might be part of it. However, the scale of the misbehavior seems extreme for a simple lack of outside time. I'm at my wit's end trying to keep things calm and prevent kids from getting hurt, let alone implement the curriculum. Also, I don't have an assistant, so I'm expected to handle things unless there's an emergency. My director is nice but unhelpful, so I can't count on any assistance there. (To be clear, I have spoken to her about the situation.) I want to quit but jobs are difficult to find in my area. Any advice would be greatly appreciated!