r/MTHFR•
BillGoldbergg

Anyone's History With Folate Dosage?

Question

I'm taking 1mg currently (Pure Encapsulations, Metafolin)

About a year ago it was confirmed on a full, elaborate nutrient panel I had a B9 deficiency. I've done a whole host of vitamins, made a lot of progress in the last year and a half. Really the only thing left is anhedonia and low energy. I'm starting to think I might need to up the dose, I've read stuff with people taking as much as 15mg.

Is 1mg considered too low of a dose?

Posted Dec 4, 2025, 9:52 PM UTC

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