How much of gltf works well?

I was playing around with raylib today, because I plan on migrating my game to Raylib + C# and I tried loading some of my models.

I encountered an issue which was that I couldn't apply a texture inside of the code(manually at runtime) if the object was loaded from the gltf format (it did work with .obj). If I apply it in blender and export it together with the .glb file, it works fine.

I wonder how much I can rely on .glb, or what features I should be careful with. Do you have any experiences regarding that?