Making lesbian friends vs. straight women friends

Do you more relaxed when developing a friendship with a girl who think might be a lesbian and not straight? I feel like I have a good sense of who might be a lesbian and not straight. I have noticed that when talking with a girl who I know is a lesbian I feel more comfortable talking to her about general topic compared to women who I know are straight. I am currently working on making friends with other women. Because I have lost all my friends since I started to date my husband.