Ultra cross pharmacodynamic resistance
Hey! I’m posting here to see if anyone has something that will help with sleep and mental health issues. But it’s a VERY long shot. I’m in the 0.01% of population who has Ultra cross pharmacodynamic desensitization/resistance. I have had blood tests done to confirm it.
I can take morphine, opioids ,benzodiazepines, zolpidem, anti depressants, stimulants, whatever in the world that’s a drug and I get NO affect physically or mentally. And I have tried every medication possible.
It’s one of the most rare things but I’m hoping someone can help.
I suffer with PTSD, dissociation identity disorder, treatment resistance depression, anxiety and paranoia. Some nights insomnia
27 / female
Is anyone there with some advice or tricks😃
I have tried every talk therapy out there but it is ineffective.
Posted Dec 7, 2025, 12:46 PM UTC