How to deal with biters in the mid-game?

Title says most of it, I currently have a pretty decent rail system and am starting to get into the logistic robots, but I feel like every time I play I have to spend an hour dealing with biters before I can get anything done. Is there a better way to kill them all at this point in the game? I just unlocked yellow science but I'm not able to make much progress on it due to my current situation.