Use Vaseline AND blister powder?

For blister prevention I’ve used Vaseline for 50k and 50 mile with no blister issues at all. I’m planning on moving up to 100k and 100 mile and would like the blister-free party to continue, but I’ve heard some people say that Vaseline wears off after a few hours, so may not be suitable for 15-30 hour events.

I’ve heard about 2Tom’s Blister powder and I’m open to trying it. I’m wondering if it’s effective to use BOTH Vaseline directly on skin and blister powder in socks, or if it’s counterproductive to use both.

Thanks