Asking for advice

hey everyone!! i’m here to ask for your help. literally any advice, do/do nots, things to prioritize/avoid, etc. i had my first MCAS anaphylactic shock episode today. it was so scary. a few days prior, my doctor prescribed me metoprolol for my POTS and i was going to take my first dose tonight after i got home from the hospital but according to my research, metoprolol is a very bad choice for managing POTS when you have MCAS as well. i’ve had POTS most of my life, along with hEDS and fibromyalgia but after a bad case of covid 2 years ago, everything got substantially worse. however, i was experiencing major life stress this past november which led to my first MCAS flare up. not anaphylactic that time but enough to offset a trail of dominos that just keep falling. i don’t know what to do. i’m ready to just give up. i’m only 19 and my entire life has been upended. my MCAS flares seem to be primarily stress activated, which sucks because i have really bad anxiety and although ive practiced anxiety management since i was a child, it definitely still impacts me physically more than i wish.

what medications have any of you taken to manage both MCAS and POTS? what techniques do you use to manage flare ups for both? what diet/exercise regime seems to have helped the most? i’m grasping at straws here. my doctors have prescribed counteracting things numerous times and im losing hope. i was so excited to try beta blockers and finally get back to a normal life but it feels like that will never happen. i’ve posted this in a few other communities as well, but any advice is welcome! im at a point where i trust fellow MCAS/POTs survivors more than doctors nowadays.

Posted Dec 29, 2025, 3:15 AM UTC

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