2-minute time management

Considering you have a 2-minute drill with 3 timeouts, how is ideally the right way to use them? I recall Brady saying he would use the first timeout at the 1-minute mark, the second around 30 seconds I believe he said, and keep the last in his pocket. I think that’s the right approach

What was tough was we had a couple of drops that pushed us to a 4th down Ben used one on. I’d have preferred to call that first timeout after Burden’s long play. How could they have managed it differently to not have run out of time?