UPDATE: HIPEC & BRaf

Update

My original post was asking for advice/experience from Redditors about HIPEC surgery when the patient has the BRaf mutation.

Original post: https://www.reddit.com/r/coloncancer/s/ZXNqmENo0A

UPDATE: My dad went to the Mayo Clinic in Rochester, MN in early December.

Under the absolutely amazing care of Dr. Grotz, he received a laparoscopic, robotic omentectomy.

His entire omentum was removed but, HIPEC was not performed. It was confirmed that there was only the single metastatic tumor.

Dr. Carr, the oncologist from the Mayo Clinic set forth a treatment protocol for him.

Next week, my dad will begin 3 months/6 cycles of Folfox and continue with the Breakwater protocol.

He has also done the initial signatera blood & tissue submission prior to surgery. He will complete a post-op/pre-chemo test next week. Then, another test after the 6 cycles are completed to help determine a forward course of action. Technically, the Signatera test next week isn’t really necessary since we intend to continue with chemo & Breakwater but; it will be good to know what we are facing with more certainty.

His Canadian Oncologist indicated that his case was palliative and that we should consider his diagnosis as terminal. She said that we were fortunate though because he was starting the “journey” from a “good” place because the metastasis was still well controlled. She went so far as to tell us that it was pointless to pursue surgery and that we were wasting our time and money!

The Mayo Clinic has given our family what feels like a miracle. I can’t say enough good things about the care he received from the Mayo Clinic.

We are filled with hope and positivity right now and I really wanted to share.

Posted Jan 8, 2026, 11:58 PM UTC

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