First time Resist Durge tips

Title says it all. I’m gonna do a resist durge campaign with a Seladrine Drow Gloomstalker assassin. What are some tips for getting the most rewarding playthough.

Handling some of the bigger storylines like The Grove? Shart and the Nightsong?

I’m entertaining killing Astarion after he tries to suck my blood. Bad idea? Mostly planning on running with Lae’zel, Shart and Gale. Might offer up Wyll as a sacrifice in act 2.

Idk anything you guys think would be helpful. I just want a good story that’s different from my usual good guy Tav