Starting Pristiq tomorrow. After being on 20mg of Lexapro for almost three years. Anyone else do this?

So I was against anti depressants for about a decade but I saw a new addiction doctor and told him I was depressed, he started me on 10mg. I’m really bad at remember to take my meds but I was working 7 days a week I kept the script in my work bag and before I knew it I took the first script and I did feel less anxious, I definitely felt a little depression but no where near the floors I was used to hitting. About a year later I thought why not increase my dose. My thinking was it’ll help me 50 percent more lol. Well over time I got worse. First of all no sex drive. Second and worst, apathy. That’s where you don’t care about anything right? Or indifference I guess. I didn’t care about even showering everyday and I used to shower twice a day. I labor, I build 400 cars a night. For me to shower once a week was disgusting first and foremost, but so unlike me. I felt numb. Like if you told the world was ending in an hour I wouldn’t have cared. I have hobbies I need them being in recovery. I lost interest in all of them even football. I have good Insurance because I work for the big 3, so they did an expensive dna test on me to see which medication would work the best. It showed up in like three columns, think green light, yellow light, red light. Lexapro showed up in yellow. Pristiq was the first one in green. I’m nervous, I hope this works. The disability woman at my doctors office said it was the best decision she made for her husband to get that test and it was a complete game changer. Anyone else switch from Lexapro to Pristiq? Thanks for listening to my story.

Posted Jan 11, 2026, 8:03 PM UTC

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