Robert House is a Synth

House graduated from CIT in the Commonwealth.

CIT is the birthplace of the Institute

The unknown player that house talked about is probably the Institute.

Robert House leaving inventions, blueprints and research behind to head to New Vegas would make sense why some of the Institute scientists could have made major leaps technologically.

The guy who made Securitrons, mind control, a anti-nuka defense system and a cryo stasis chamber to live forever seems to have the knowledge that would be easily sought after before and after the bombs fell by these CIT students/scientist's.