LSD microdosing with ADHD: 5 mcg did nothing, 10 mcg caused brain fog?

Question: LSD

Hey everyone, I could really use your tips, opinions, experiences… 🙏

I’ve been experimenting with LSD microdosing for a few weeks now. Background is that I have ADHD and depression / exhaustion but honestly it’s mainly about curiosity, experimenting and interest.

I only dose once a week on the weekend, on a day when I don’t have to drive and can keep the day completely off any duties.

I started with 5 mcg and to be honest I don’t think I felt anything at all. I tried that twice, one week apart. Last week I tried 10 mcg for the first time and I have to say it was really weird: no psychedelic effects at all, but mild brain fog and actually increased tiredness. Could it be that I react paradoxically because of ADHD? It’s not a stimulant, I know, but I do know from myself that I often react paradoxically to substances.

I did some research and depending on the nervous system it actually seems possible that too low of a dose can feel rather unpleasant…?

So my question now: has anyone Else experienced this effect? Do you think I should try 15 to 20 mcg on my next MD day? That wouldn’t really be microdosing anymore, but somehow it feels like sticking with 5 mcg is just a waste…?

Posted Jan 17, 2026, 10:42 PM UTC

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