Looking for a detergent with enzymes (SLS-free?)

I’ve been using Persil Advanced Clean for a while now, and while it seems to be working better than some other detergents I've used, I heard that it has no liapse enzyme.

I would like to have something that cleans really well, and I don’t mind paying a little bit more if it‘s worth it. However, I would like it to be easy to get (in common stores or Amazon) so niche stuff isn’t preferable.

I see a lot of people recommending 365 Sport, but since that has SLES I’ve been hesitant about it. This brings me to a bigger question; do sulfates really affect your skin (breakouts, etc) when they are in detergents? I do use citric acid in the softener department, which I heard washes out the detergent a lot more than just rinsing does.

If they are likely to still affect skin after rinsing, what other detergents with at least lipase should I look into and how do they compare to 365 Sport? Would it be worth getting a different detergent without SLES but still using the 365 Sport for heavily sweated-in clothes?

Thanks!

Posted Jan 30, 2026, 5:13 AM UTC

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