What is the highest dose of prednisone you ever had?

Question

I’m on day 8 of taking 60mg of Prednisone, but it doesn’t seem to be helping much at the moment. The last times, I started with 60mg and it was fine but it doesn’t seem to be effective anymore. I’m going to see my GI on Monday, but I wanted to ask which doses are helpful for you. How high are your doses? Am I developing an immunity to this medication?

The highest I‘ve ever had were 1000mg per day for three days (3000mg in total), but this was for another condition.

Posted Feb 7, 2026, 10:58 PM UTC

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